林啟萬合聘教授的個人資料 - Profile of Chii-Wann Lin

林啟萬 Chii-Wann Lin

國立臺灣大學電機工程學系 合聘教授
台大工研院合設奈米研究中心 主任
Jointly Appointed Professor, Department of Electrical Engineering, National Taiwan University
NTU-ITRI Nano Center, Director

主要研究領域:

生物微感測器與系統、生醫晶片、生醫光電、類神經網路、醫材法規

Major Research Areas:

Bioelectronics、Biomedical Micro sensors and System、Biochip、Biomedical Optics、Artificial Neural Networks, Regulatory Affairs

研究領域摘要:

本研究室致力於利用近年來國內半導體產業設計、製作、整合能力與基礎的完善，期使生醫微型感測器的研發工作能有更精確、價廉、方便使用的產品。方向包括有：積體電路設計、生物感測器原理與設計製作、精微機電技術系統整合、與神經系統之工程應用。目前之研究領域包括蓋生醫光學檢測、電化學檢測、呼吸流量檢測、類神經網路理論與矽神經元。主要計畫為表面電漿子共振之理論發展與元件之設計製作，嶄新之研究方向包括主動式表面電漿子共振與表面電漿波傳導於分子流速之檢測，在奈米科技上亦發展金微粒強化表面電漿共振與具表面奈米結構之壓印細胞晶片，具體方向為光學式生醫晶片與檢測系統於疾病診斷與藥物篩選之應用。為達實用之目的，亦同時致力建立與實現ISO 17025之實驗室品質系統，配合AAMI/ANSI, IEC相關醫療儀器標準，在CNLA架構下建立醫療儀器、器材相關之檢驗實驗室，以利國內自行研發之檢驗儀器及技術得以順利上市。希望不僅在實質的研發品質管理上獲得能力提升，更進一步促使國內之醫學工程研發得以具有產業發展的機會。

Research Summary:

In view of the superior advantages of Taiwan on microelectronics design and available fabrication resources, this laboratory is dedicated to research and development of medical microsensors and devices with available facilities and technologies for better and cheaper products. The extended research directions include integrated biosensor design, BioMEMS, system integration, and neuronal inspired intelligent algorithms, especially on biomedical optics, electrochemical sensor, respiratory flow sensor, ANN, and silicon neurons. Current funding focus on the design and development of novel Surface Plasmon Resonance (SPR) devices, including ActiveSPR and Time-of-Flight SPW (TOFSPW) for surface velocity measurement. Nanoparticle enhanced SPR and surface contact printing with defined nano features for cell chip are also under development. The target applications of these novel optical device and system are disease diagnostic and drug screening. To facilitate the linkage between academic research and industrial development, we also dedicate to establish testing facilities for the safety of medical devices. ISO 17025 is adapted as the laboratory quality system to harmonize with CNLA. The long-term objective is to promote the quality and quantity of novel medical devices for native medical device industry and thus better health care through operatable medical standards and regulations.

Photo of Chii-Wann Lin

代表性著作 Selected Publication

  1. Da-Sin Wang, C.-W. Lin*, “Surface plasmon effects on two photon luminescence of gold nanorods,” Optics Express, 17, 11350, Jul. 2009
  2. Hui-Hsin Lu, C.-W. Lin*, Tzu-Chien Hsiao, Chih-Kung Lee, Su-Ming Hsu, “Nanopatterning on Silicon Wafers Using AFM-Based Lithography—for Solar Cells,” Journal of Nanoscience and Nanotechnology, 9, 1696-1700, 2009
  3. Hui-Hsin Lu; Chia-Yu Lin; Tzu-Chien Hsiao; Yueh-Yuan Fang; Kuo-Chuan Ho; Dongfang Yang; Chih-Kung Lee; Su-Ming Hsu, C.-W. Lin*, “Electrical Properties of Single and Multiple PEDOT nanowires for Sensing Nitric Oxide Gas,” Analytica Chimica Acta, ACA-08, 2257R1, 2009
  4. Yao-Joe Yang, Yu-Jie Huang, Hsin-Hung Liao, Tao Wang, Pen-Li Huang, Chii-Wan Lin, Yao-Hong Wang, Shey-shi Lu,, “A Release-on-Demand Wireless CMOS Drug Delivery SoC Based on Electrothermal Activation Technique,” ISSCC 2009, D17-02, 2009
  5. 8. C. Y. Lin, P. C. Nien, W. Y Feng, C. W. Lin, J. Tunney and K. C. Ho, “Chemiresistive NO Gas Sensor Based on Zinc Oxide Nanorods,” Journal of bionanoscience, in press, 2008
  6. Henghua Deng, Dongfang Yang, Bo Chen, C.-W. Lin, “Simulation of Surface Plasmon Resonance of Au-WO(3-x) and Ag-WO(3-x) Nanocomposite Films,” Sensors & Actuators B, 134, 502-509, 2008
  7. Szu-Yuan Lee, Chun-Nan Lee, Mark Holl, Deirdre R Meldrum, C.-W. Lin, “Compact Optical Diagnostic Device for Isothermal Nucleic Acids Amplification,” Sensors & Actuators B: Chemcial, 133, 493-501, 2008
  8. Yan-You Lin, C.-W. Lin*, Lung-Jieh Yang, “MICRO-VISCOMETER BASED ON ELECTRO-WETTING ON DIELECTRIC,” Electrochimica Acta, 52, 2876-2883, 2007
  9. Nan-Fu Chiu, Chun Yu, Shou-Yu Nien, Jiun-Haw Lee, Hung-Chun Chang, Chieh-Hsiung Kuan, Kuang-Chong Wu, Chih-Kung Lee and C.-W. Lin*, “Enhancement and Tunability of Active Plasmonic by Multilayer Grating Coupled Emission,” Optics Express, 15, 11608-11615, 2007
  10. Szu-Yuan Lee, Chun-Nan Lee, Holl Mark, Deirdre R. Meldrum, C.-W. Lin, “Efficient, Specific, Compact Hepatitis B Diagnostic Device:Optical Detection of the Hepatitis B Virus by Isothermal Amplification,” Accepted by Sensors and Actuators B:Chemical Sensors and Actuators B, 127, 598–605, 2007
  11. Nan-Fu Chiu, C.-W. Lin*, Jiun-Haw Lee, Chieh-Hsiung Kuan, Kuang-Chong Wu, Chih-Kung Lee, “Enhanced luminescence of organic/metal nanostructure for grating coupler active long-range surface plasmonic device,” Applied Physic Letters, 91, 2007
  12. Szu-Yuan Lee, Chun-Nan Lee, Holl Mark, Deirdre R. Meldrum, Chih-Kung Lee, C.-W.Lin*, “Optimal Hepatitis B Virus Primer Sequence Design for Isothermal Amplification” Biomedical Engineering, Applications, Basis, Communications,” EI, 19, 137-144, 2007
  13. Da-Shin Wang, C.-W. Lin, “Density-dependent optical response of gold nanoparticle monolayers on silicon substrates,” Optics Letter, 32, 2128–2130, 2007
  14. C.-W. Lin, Kuo-Ping Chen, Min-Chi Su, Tze-Chien Hsiao, Sue-Shan Lee, Shiming Lin, Xue-Jing Shi, Chih-Kung Lee, “Admittance Loci Design Method for Multilayer Surface Plasmon Resonance Devices,” Sensors and Actuators B: Chemical, 117, 219, 2006
  15. K.-H. Chen, T.-F. Chang, Y.-C. Chen, C.-W. Lin, “A Neonatal Facial Image Scoring System (NFISS) for Pain Response Studies,” Accepted by BME ABC, 2005
  16. C.-W. Lin, K.-P. Chen, S.-M. Lin, C.-K.Lee, “Design and Fabrication of an Alternative Dielectric Multilayer device for Surface Plasmon Resonance Sensor,” Accepted by Sensors and Actuators B: Chemical, 2005
  17. Jian-Ming Chen, Jhen-Gang Huang, C.-W. Lin, “The Design and Fabrication of Two-Dimension Multi-Electrodes Array Chip and System,” IEEE EMBS 2004, San Francisco, Sept. 2004
  18. Ya-ling Lo, and C.-W. Lin, “Investigation of size-induced optical enhancement utilizing nanoparticle based surface Plasmon resonance,” the Asia-Pacific Conference of Transducers and Micro-Nano Technology (APCOT MNT 2004), Sapporo, Japan (Accepted for oral presentation), Jul. 2004
  19. C.-W. Lin, K.-P. Chen, H.-L. Lee, C.-C. Yang, C.-K. Lee, “Bio-Plasmonics,” APBP2004, Taipei, 2004
  20. F-R Liao, C.-A. Chen, S.-S. Lu, N.-F. Chiu, C.-W. Lin, J.-Y. Li, C.-N. Chien, F.-S. Jaw, J.-M. Wang, L.-J. Yang, T.-C. Hsiao, and C.-K. Lee, “An Implantable Integrated SIGE FM Transmitter for HRV Biotelemetry,” IEEE BioCAS2004, S1.8-9 – 11. (EI), 2004
  21. C.-W. Lin, C.L. Lee, W. S. Wang, C.-K. Lee, “A Novel Cross-Reference Dual-Window SPR sensor based on single silica optical waveguide,” APBP2004, Taipei, 2004
  22. Zhi-Hsiang Song, C.-W..Lin, Chih-Kuang, Lee, “A Novel Biochip Detection System Based on Lateral SPR Wave Propagation Theory,” IEEE SENSORS 2004,, Vienna, 2004
  23. C.-W. Lin, H.-C. Lai,C.-K. Lee, S.-M. Lin, “SPR Biochip and Detection System for Tuberculosis Bacillus,” WCCBME 2004, Beijing, 2004
  24. C.-W. Lin, M.-F. Lee, Y.-F. Yang, C.-C. Wu, “Surface Modification of Bio-MEMS Micro-device with Conductive Polymer,” WCCBME 2004, Beijing, 2004