Crystalline fiber based broadband light sources: including the next generation optical amplifier in the 1.2-1.6-μm band and the tunable laser and high-brightness emission in the 0.6-1.4-μm wavelength range,
In-vivo biomedical optical imaging: Using our proprietary crystalline fiber based optical coherence tomography system, submicron resolution has been achieved for real-time cell/tissue analyses. Dynamic bio-imaging is now utilized on organ anatomy and blood flow for early detection/diagnosis of diseases and cancers,
Generative AI: trustworthy 3D virtual histopathology
B.S.
, Dept. Elec. Eng., National Taiwan University, 1986
M.S.
, Dept. Elec. Eng., University of Maryland, College Park, 1990
Ph.D.
, Dept. Elec. Eng., University of Maryland, College Park, 1993
Address
EE2-341,
Department of Electrical Engineering,
National Taiwan University,
Taipei 106, Taiwan
C. H. Liu, Y. W. Lee, Y. S. Chen, Y. C. Chen, and S. L. Huang, “Deep generative network for cellular-resolution optical coherence tomography image denoising,” IEEE Journal of Selected Topics in Quantum Electronics, 32, No. 4, 6800311, Jul. 2026
C. H. Liu, L. W. Fu, S. W. Chang, J. Y. Wang, Y. J. Wang, Y. H. Wu, H. H. Chen, and S. L. Huang, “Quantitative assessment of in vivo nuclei and layers of human skin by deep learning-based OCT image segmentation,” Biomedical Optics Express, 16, No. 4, 1528, Apr. 2025
Y. H. Hsiao, K. C. Chen, C. L. Chien, W. T. Huang, N. Majewska, M. Kamiński, S. Mahlik, G. Leniec, E. Mijowska, S. L. Huang, and R. S. Liu, “Broadband near-infrared Cr4+-doped garnet phosphors through divalent calcium charge compensation for advanced crystal fiber amplifiers,” Advanced Optical Materials, 12, 2401543, 1, Dec. 2024
L. W. Fu, C. H. Liu, M. Jain, C. J. Chen, Y. H. Wu, S. L. Huang, and H. H. Chen, “Training with uncertain annotations for semantic segmentation of basal cell carcinoma from full-field OCT images,” IEEE Transactions on Medical Imaging, 43(3), 1060, Mar. 2024
C. H. Liu, L. W. Fu, H. H. Chen, and S. L. Huang, “Toward cell nuclei precision between OCT and H&E images translation using signal-to-noise ratio cycle-consistency,” Computer Methods and Programs in Biomedicine, 242, 107824, Oct. 2023
S. T. Tsai, C. H. Liu C. C. Chan, Y. H. Li, S. L. Huang, and H. H. Chen, “H&E-like staining of OCT images of human skin via generative adversarial network,” Applied Physics Letters, 121, 134102, Sept. 2022
T. S. Ho, M. R. Tsai, C. W. Lu, H. S. Chang, and S. L. Huang, “Mirau-type full-field optical coherence tomography with switchable partially spatially coherent illumination modes,” Biomedical Optics Express, 12, No. 5, 2670-2683, Apr. 2021
T. S. Ho, P. Yeh, C. C. Tsai, K. Y. Hsu, and S. L. Huang, “Spectroscopic measurement of absorptive thin films by spectral-domain optical coherence tomography,” Optics Express, 22, No. 5, pp. 5675–5683, 2014