Emeritus Professors

黃念祖 Huang, Nien-Tsu

  • Assistant Professor, Department of Electrical Engineering, National Taiwan University
  • Ph.D. University of Michigan, 2012
  • M.S. National Taiwan University , 2005
  • B.S. National Taiwan University , 2003
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Major Research Areas

Bio-MEMS, Optical-MEMS, Microfluidics, Bio-sensing, Cell Manipulation in Microenvironment, Micro/Nano Fabrication Techniques.

Research Summary

Our lab is focusing on developing integrated electrical, optical and mechanical miniaturized fluidics and sensors for biological applications, such as cellular biology, drug screening, and disease diagnosis. You can find more of our current research projects in our lab website. 

    黃念祖助理教授於2003年及2005年取得台灣大學機械工程系學士和應用力學所碩士學位,畢業後前往美國密西根大學(University of Michigan, Ann Arbor)取得機械工程學博士學位。黃教授於2013年8月返台,目前擔任台大電機系和生醫電資所合聘教師。黃教授取得博士學位後,於密西根大學及附屬墨茲兒童醫院擔任博士後研究員進行小兒敗血症和器官移植免疫系統的研究。他的研究成果包含設計微小化生醫晶片和搭配之光學系統以達到快速檢測和少量化樣本需求,上述成果獲得美國國衛院(National Institutes of Health)、國科會 (National Science Foundation) 等數項研究計畫補助。同時間他也多次參與知名國際微機電和生醫晶片會議並發表超過15篇生醫微奈米系統期刊和國際會議論文。他亦擔任專書”光微奈米致動器科技”(Optical Nano and Micro Actuator Technology) 章節作者,並擁有數項微流體系統專利待核定中。

    Nien-Tsu Huang received his B.S. in Mechanical Engineering and the M.S. in Applied Mechanics from National Taiwan University, Taipei, Taiwan, in 2003 and 2005.  He received the Ph. D. degree in Mechanical Engineering at the University of Michigan, Ann Arbor, in 2012. Following a post-doctoral training in the Mechanical Engineering and C.S. Mott Children's Hospital at the University of Michigan, he joined the Graduated Institute of Biomedical Electronics and Bioinformatics and the Department of Electrical Engineering at National Taiwan University in 2013. During his post doctoral training, he developed integrated microfluidic devices and customized optical system for investigating immune system of pediatric sepsis patients. These research results had been published in several prestigious journal and conference paper. Besides, he also got various research grants from National Institutes of Health (NIH) and National Science Foundation (NSF) for developing integrated optofluidic platforms projects. 

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Journal articles & book chapters

1. 1. A. B. Simon, J. P. Frampton, N. -T. Huang, S. Paczesny, K. Kurabayashi, S. Takayama,, “Aqueous two-phase systems enable multiplexing of homogeneous immunoassays” , TECHNOLOGY , Vol. 2 , 176-184, Jun. 2014

2. N.–T. Huang, H. Zhang, M. –T. Chung, J. H. Seo, and K. Kurabayashi, “Recent Advancements in Optofluidics-Based Single-cell Analysis: Fully Optical On-Chip Cellular Manipulation, Treatment, and Property Detection” , Lab on a Chip , Vol. 14 , 1230-1245-, Mar. 2014

3. B.-R. Oh, N.-T. Huang, W. Chen, J. Seo, P. Chen, T. T. Cornell, T. P. Shanley, J. Fu, and K. Kurabayashi, “Integrated Nanoplasmonic Sensing for Cellular Functional Immunoanalysis Using Human Blood” , ACS Nano , Vol. 8 , 2667-2676, Feb. 2014

4. W. Chen*, N. -T. Huang*, B. -R. Oh, R. H. W. Lam, R. Fan, T. T. Cornell, T. P. Shanley, K. Kurabayashi, and J. Fu, “Surface-micromachined microfiltration membranes for efficient isolation and functional immunophenotyping of subpopulations of immune cells” , Advanced Healthcare Materials , Vol. 2(7) , 965-975-, Jul. 2013

5. W. Chen*, N.-T. Huang*, X. Li, Z. Yu, K. Kurabayashi, and J. Fu, “Emerging Microfluidic Tools for Functional Immunophenotyping: A New Potential Paradigm for Immune Status Characterization” , Frontiers in Oncology , Vol. 3 , 98-, Apr. 2013

6. N. -T. Huang*, W. Chen*, B. -R. Oh, T. T. Cornell, T. P. Shanley, J. Fu, and K. Kurabayashi, “An integrated microfluidic platform for in-situ cellular cytokine secretion immunophenotyping” , Lab on a Chip , Vol. 12 , 4093-4101-, Jul. 2012

7. Y. -C. Tung, N. -T. Huang, B. -R. Oh, B. Patra, C. -C. Pan, T. Qiu, P. K. Chu, W. Zhang, and K. Kurabayashi, “Optofluidic detection for cellular phenotyping” , Lab on a Chip , Vol. 12 , 3552-3565-, Jun. 2012

8. N. -T. Huang, S. C. Truxal, Y. -C. Tung, A. Y. Hsiao, G. D. Luker, S. Takayama, and K. Kurabayashi, “Multiplexed spectral signature detection for microfluidic color-coded bioparticle flow” , Analytical Chemistry , Vol. 82 , 9506-9512-, Oct. 2010

9. N. -T. Huang, S. C. Truxal, Y. -C. Tung, A. Hsiao, S. Takayama, and K. Kurabayashi, “High-Speed Tuning of Visible Laser Wavelength Using a Nanoimprinted Grating Optical Tunable Filter” , Applied Physics Letters , Vol. 95 , 21106-, Nov. 2009

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Conference & proceeding papers:

1. Da-Han Kuan, I-Shun Wang, Chih-Ting Lin, Nien-Tsu Huang, “A MULTI-FUNCTIONAL MICROFLUIDIC PLATFORM INTEGRATED WITH DUAL CMOS POLYSILICON NANOWIRE SENSOR FOR SIMULTANEOUS HEMOGLOBIN AND GLYCATED HEMOGLOBIN DETCTION” , μTAS 2015 , Gyeongju, Korea , Oct. 2015

2. Yu-Shin Chang, Frank Shyu, Kai-Wei Chang, Mon-Hsun Tsai, Nien-Tsu Huang, “Point Mutation Detection by Microfluidic DNA Microarray for Long QT Syndrome” , Optofluidics 2015 , Taipei, Taiwan , Jul. 2015

3. Sheng Yang, Chao-Han Yang, Nien-Tsu Huang, “Developing multiple microfiltration membranes microfluidics for monitoring early-stage inflammation of peritoneal dialysis patients” , Optofluidics 2015 , Taipei, Taiwan , Jul. 2015

4. Po-Yen Lu, Che-Pin Chang, Nien-Tsu Huang, “Developing integrated optofluidic platform for cellular immunophenotyping” , Optofluidics 2015 , Taipei, Taiwan , Jul. 2015

5. Yeu-Farn Shih, Nien-Tsu Huang, Chih-Kung Lee, “Capturing CD4 cells using a functionalized circular microfluidic device and glutaraldehyde as biolinker for tuberculosis detection and diagnosis” , SPIE Phonics West , San Francisco, USA , Feb. 2015

6. Weiqiang Chen, Nien-Tsu Huang, Bo-Ram Oh, Timothy T. Cornell, Thomas P. Shanley, Katsuo Kurabayashi, and Jianping Fu, “Microfluidic immunophenotyping assay platform for immunomonitoring of subpopulations of immune cells” , Proc. 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences (μTAS 2013) , Freiburg, Germany , Oct. 2013

7. Bo-Ram Oh, Nien-Tsu Huang, Weiqiang Chen, Jungwhan Seo, Jianping Fu, and Katsuo Kurabayashi, “Localized surface plasmon resonance (LSPR) optofluidic biosensor for label-free cellular immunophenotyping” , Proc. 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences (μTAS 2013) , Freiburg, Germany , Oct. 2013

8. N. -T. Huang, W. Chen, B. -R. Oh, J. Fu, and K. Kurabayashi, “An integrated microfluidic platform for in-situ cellular cytokine secretion immunophenotyping” , The 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2012 , Okinawa, Japan , Nov. 2012

9. W. Chen, N. -T. Huang, K. Kurabayashi, and J. Fu, “Surface Micromaching Polydimethylsiloxane(PDMS) for Microfluidic Biomedical Application” , The 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2012 , Okinawa, Japan , Nov. 2012

10. N. -T. Huang, S. Truxal, Y. -C. Tung, and K. Kurabayashi, “Multi-Spectral Tunable Excitation Fluorescence Microscopy with a Nanoimprinted PDMS-on-Silicon Grating Optical Filter” , The 25th International Conference on Micro Electro Mechanical Systems IEEE MEMS 2012 , Paris, France , Jan. 2012

11. S. C. Truxal, N. -T. Huang and K. Kurabayashi, “A Nano Grating Tunable MEMS Optical Filter for High-Speed On-Chip Multispectral Fluorescent Detection” , Proc. the 31st Annual International Conference of IEEE Engineering in Medicine and Biology Society , Minneapolis, MN , Sep. 2009

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Books:

1. K. Kurabayashi, N. -T. Huang, and Y.-C. Tung, “Optical Nano and Micro Actuator Technology, Chapter 16: Multiscale, Hierarchical Integration of Soft Polymer Micro- and Nano Structures into Optical MEMS” , CRC press , 9781439840535 , 639 , USA, Nov. 2012

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